Clinical efficacy of Colgate® Sensitive Pro-ReliefTM toothpaste
F Ayad, N Ayad, YP Zhang, W DeVizio, D Cummins, and LR Mateo
RESULTS:
When used over a period of 8 weeks, the novel toothpaste containing arginine and MFP in a calcium carbonate base significantly reduced dentine hypersensitivity (p < 0.05) in response to both the tactile and air blast stimuli. Compared to the commercial toothpaste with 2% potassium ion and NaF, the arginine containing toothpaste was significantly (p <0.05) more effective in reducing hypersensitivity scores after 2, 4, and 8 weeks of use (16.2%, 22.4%, and 21.4% for tactile stimuli; 16.2%, 29.2% and 63.4% for air blast stimuli).
CONCLUSION:
A new toothpaste with 8% arginine, calcium carbonate and 1450 ppm fluoride (MFP) provided significantly (p < 0.05) greater dentine hypersensitivity relief after 2, 4, and 8 weeks of use than a desensitising toothpaste containing 2% potassium ion and 1450 ppm fluoride (NaF).