Colgate® Sensitive Pro-Relief™ Toothpaste With Pro-Argin™ Technology


Delivers both instant* and lasting hypersensitivity relief together with the recommended fluoride level for caries prevention (1450ppm F).


  • Ingredients

    Active ingredients

    Arginine 8% w/w, Sodium Monofluorophosphate 1.1% w/w (1450ppm F)



    Calcium Carbonate, Water, Sorbitol, Arginine Bicarbonate, Sodium Lauryl Sulfate, Flavor, Sodium Monofluorophosphate, Cellulose Gum, Sodium Bicarbonate, Potassium Acesulfame, Sodium Silicate, Xanthan Gum, Sucralose, CI 77891

  • Mode of Action

    Pro-Argin technology plugs and seals open dentine tubules with a calcium-rich mineral layer.

  • Proof of Efficacy

    Clinical efficacy of Colgate® Sensitive Pro-ReliefTM toothpaste

    F Ayad, N Ayad, YP Zhang, W DeVizio, D Cummins, and LR Mateo


    When used over a period of 8 weeks, the novel toothpaste containing arginine and MFP in a calcium carbonate base significantly reduced dentine hypersensitivity (p < 0.05) in response to both the tactile and air blast stimuli. Compared to the commercial toothpaste with 2% potassium ion and NaF, the arginine containing toothpaste was significantly (p <0.05) more effective in reducing hypersensitivity scores after 2, 4, and 8 weeks of use (16.2%, 22.4%, and 21.4% for tactile stimuli; 16.2%, 29.2% and 63.4% for air blast stimuli).


    A new toothpaste with 8% arginine, calcium carbonate and 1450 ppm fluoride (MFP) provided significantly (p < 0.05) greater dentine hypersensitivity relief after 2, 4, and 8 weeks of use than a desensitising toothpaste containing 2% potassium ion and 1450 ppm fluoride (NaF).

  • Other Variants

    1. Colgate® Sensitive Pro-Relief Repair & Prevent Toothpaste
    2. Colgate® Sensitive Pro-Relief Enamel Repair Toothpaste
    3. Colgate® Sensitive Pro-Relief Gum Care Toothpaste
    4. Colgate® Sensitive Pro-Relief +Whitening Toothpaste
    5. Colgate® Sensitive Pro-ReliefComplete Protection Toothpaste